withdrawal confounding

Estimating Risk of Antidepressant Withdrawal from a Review of Published Data

This article – from Mark Abie Horowitz, Adele Framer, Michael P. Hengartner, Anders Sørensen & David Taylor – has been published in the journal CNS Drugs. The abstract says: “Adaptation of the brain to the presence of a drug predicts withdrawal…
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Prophylactic effects or withdrawal reactions? An analysis of time-to-event data from antidepressant relapse prevention trials submitted to the FDA

Author: Editorial 20th August 2021 0 Comments

Prof. Peter Gøtzsche has tweeted : “When you stop taking a depression pill and feel bad, psychiatrists tell you that you have relapsed. Not so. By far most, perhaps even all your troubles, are withdrawal symptoms … Never stop abruptly. This…
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collaborative practice

antidepressants, depression, Food & Drug Administration (FDA), Peter Gøtzsche, placebo, prophylactic effects, relapse prevention, Research, Therapeutic Advances in Psychopharmacology, withdrawal confounding

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Estimating Risk of Antidepressant Withdrawal from a Review of Published Data

Prophylactic effects or withdrawal reactions? An analysis of time-to-event data from antidepressant relapse prevention trials submitted to the FDA