serotonin

The Serotonin Zombie: Authors of New Study Try to Breathe New Life into the Dead

Peter Simons reports for Mad in the UK: “In June, Joanna Moncrieff and others had appeared to put the final dagger into the low serotonin theory of depression (the so-called ;chemical imbalance’ theory). They reviewed fifty years of research into the…
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Response to Criticism of Our Serotonin Paper

This article by Joanna Moncrieff and Mark Horowitz has been published by Mad in America. It begins: “We recently published a  paper  finding that the serotonin hypothesis of depression (the idea that depression is caused by low serotonin or reduced serotonin activity)…
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“Clear evidence” for serotonin hypothesis of depression?

This post by Dr. Eiko Fried has been published on his blog site Measurement, modeling & complexity of mental health. It begins: “There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of…
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How to take the news that depression has not been shown to be caused by a chemical imbalance

This article is from psychiatrist Dr. Joanna Moncrieff. It begins: “For decades people have been told that depression is caused by a serotonin deficiency. This was the rationale behind the introduction of the SSRI (Selective Serotonin Reuptake Inhibitor) antidepressants in the…
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A Decisive Blow to the Serotonin Hypothesis of Depression

This article by Christopher Lane has been published in Psychology Today. It begins: “Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of  depression —reduced and simplified by pharma marketing to the ‘chemical imbalance’…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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Primum non nocere: an evolutionary analysis of whether antidepressants do more harm than good

This review has been published on the PubMed website. The abstract says: “Antidepressant medications are the first-line treatment for people meeting current diagnostic criteria for major depressive disorder. Most antidepressants are designed to perturb the mechanisms that regulate the neurotransmitter serotonin…
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Time for Some Serious Thought about ‘Antidepressants’

This blog post (2016) from Peter Hitchens has been published in the Daily Mail. It begins: “I expect to have more to say about this, but today’s BMJ? UCL/ Nordic Cochrane Centre analysis of research on ‘antidepressants’ should surely change the terms…
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