depression
The Maudsley Guidelines for De-prescribing

The Maudsley Deprescribing Guidelines (published by Wiley) will be out in a couple of months. Co-authored by David M. Taylor and Mark Horowitz, it will contain evidenced-based taper regimens for all antidepressants and practical advice on how to do it….
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No benefit of antidepressants in inpatient treatment of depression. A longitudinal, quasi-experimental field study

This article by Reinhard Maß, Kerstin Backhaus, Katharina Lohrer, Michael Szelies and Bodo K. Unkelbach has been published in Psychopharmacology. The abstract says: “Rationale Antidepressants (AD) are mostly considered indispensable for the treatment of major depression. The vast majority of…
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A Neuroscientist Evaluates the Standard Biological Model of Depression

This research article by Peter Sterling (Professor of Neuroscience) has been published by Mad in America. It begins: “Abstract Neuroscientists widely hypothesize that ‘depression’ arises from a brain disorder caused by some defect in a specific neural pathway. If so, we might identify…
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Not My Words, Not My Story by Julia Buxton
Framing Depression as a Functional Signal Rather than a Disease Promotes Hope and Reduces Stigma, Study Finds
Are antidepressants effective in the treatment of depression in the elderly? A critical umbrella review on reviews, methods, and future perspectives

This umbrella review from Dr. Michael F. Hvidberg has been published in the journal Mental Health Science. The abstract says: “The elderly are currently the most frequent users of antidepressants across ages, despite having a high risk of adverse effects (AEs). This literature…
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Placebo effects and the Royal College of Psychiatrists

This twitter thread from the Royal College of Psychiatrists concerns a presentation called “The placebo effect: insights for translational research and clinical practice”. The thread includes the following: “… 50 years of drug trials for anxiety disorders. Very few have been successful…
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