depression

The Serotonin Zombie: Authors of New Study Try to Breathe New Life into the Dead

Peter Simons reports for Mad in the UK: “In June, Joanna Moncrieff and others had appeared to put the final dagger into the low serotonin theory of depression (the so-called ;chemical imbalance’ theory). They reviewed fifty years of research into the…
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Depression Not So “Treatment-Resistant” After Psychodynamic Psychotherapy

“Researcher finds Intensive Short-Term Psychodynamic Psychotherapy reduced depressive symptoms in patients who did not improve with pharmacological treatment.“ This report by Dr. José Giovanni Luiggi-Hernández has been published by Mad in America. It begins: “A recent study published in Psychotherapy suggests that Intensive…
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Seven lifestyle changes that lower risk of depression

Sarah Knapton reports for The Telegraph: “Moderate drinking and a good night’s sleep are among seven healthy lifestyle changes that can more than halve the risk of depression, scientists have found. Experts at the University of Cambridge examined health data from…
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Beyond the Chemical Imbalance Theory of Depression: An Interview with Prof. Joanna Moncrieff

This interview , conducted by Justin Garson, has been published in Psychology Today. It begins: “KEY POINTS In 2022, a large review led by Joanna Moncrieff showed the ‘serotonin theory of depression’ to be groundless. Her review puts into question our…
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These habits can cut the risk of depression in half, a new study finds

“I think the biggest surprise is that if you have a favorable lifestyle, you can reduce the risk of your getting depression by 57%, which is really quite a massive amount” Barbara Sahakian (clinical psychologist and neuroscientist at the University…
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Psychobiotics and the need for better interventional data

This article (with relevance to mental health) has been published in BMC Medicine. It begins: “Gut microbiota composition has been associated with multiple health outcomes: various studies employing predictive genetic studies and randomised controlled trials suggest this is the case. More…
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Prenatal Antidepressant Exposure and Offspring Brain Morphologic Trajectory

This research paper has been published in JAMA Psychiatry. Key Points: Question: Is intrauterine exposure to selective serotonin reuptake inhibitors (SSRIs) and prenatal or postnatal depressive symptoms associated with brain morphologic trajectory in offspring? Findings: In this cohort study of 3198 mother-infant…
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Associations between constructs related to social relationships and mental health conditions and symptoms: an umbrella review

This review has been published in BMC Psychiatry. The abstract says: “Background: Loneliness and social isolation are increasingly recognised as prevalent among people with mental health problems, and as potential targets for interventions to improve quality of life and outcomes, as…
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Acceptability and optimisation of resources to support antidepressant cessation: A qualitative think-aloud study with patients

This study by Suzanne McDonald, Katharine Ann Wallis, Mark Horowitz, Esther Mann, Vilany Le and Maria Donald has been published in the British Journal of General Practice. The abstract says: “Background: Stopping long-term (>12 months) antidepressants can be difficult for patients…
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Wishful thinking: antidepressant drugs in childhood depression

This paper from Anne Tonkin and Jon Jureidini has been published in the British Journal of Psychiatry. It begins: “The use of selective serotonin reuptake inhibitors (SSRIs) in children under 18 years old increased ten-fold (from 0.5 to 4.6 per 1000)…
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